Bone Cancer

Bone cancer.

Primary bone cancers are extremely rare neoplasms, accounting for fewer than 0.2% of all cancers. The evaluation and treatment of patients with bone cancers requires a multidisciplinary team of physicians, including musculoskeletal, medical, and radiation oncologists, and surgeons and radiologists with demonstrated expertise in the management of these tumors. Long-term surveillance and follow-u...

Cancer induced bone pain.

Cancer and bone.

Bone Cancer in Greyhounds

Primary bone neoplasms are common in dogs. Most primary bone tumors in dogs are malignant, in that they usually cause death as a result of local infiltration (e.g., pathologic fractures or extreme pain leading to euthanasia) or metastasis (e.g., pulmonary metastases in osteosarcoma). Neoplasms that metastasize to the bone are extremely rare in dogs; some malignant tumors that occasionally metas...

Biology of bone cancer pain.

Bone cancer pain is a devastating manifestation of metastatic cancer. Unfortunately, current therapies can be ineffective, and when they are effective, the duration of the patient's survival typically exceeds the duration of pain relief. New, mechanistically based therapies are desperately needed. Study of experimental animal models has provided insight into the mechanisms that drive bone cance...